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  • Ciliopathies are a group of diseases that affect kidney and retina among other organs. We identify a missense mutation in VPS15 in a family with a ciliopathy phenotype and show that deside being required for trafficking and autophagy, VPS15 regulates primary cilium length in human fibroblasts.
  • Campustag Lehre hoch Forschung: Bettina Fleck has been honoured for her excellent research in anti MRSA drugs
  • CyberChampion Awards 2016: init innovation award for vasQlab. The team of Prof. Dr. Ute Schepers and Christoph Grün convinced the jury with innovative body-on-a-chip systems for pharmaceutical research.
Selected publications
  • Orian-Rousseau, V. / Matzke-Ogi, A. (2017)
    Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets
    Theranostics, 7 (2), 482–492. doi:10.7150/thno.16816

  • Thomas Dickmeis (2016)
    Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids
    PLoS Genet 12(12): e1006512. doi:10.1371/journal.pgen.1006512

  • Stefan Bräse (2016)
    Genetic code expansion for multiprotein complex engineering
    Nature Methods | Published online 17 October 2016 | doi:10.1038/nmeth.4032
    press release

  • Pavel Levkin (2016)
    Fabrication of Hydrogel Particles of Defined Shapes Using Superhydrophobic-Hydrophilic Micropatterns
    DOI: 10.1002/adma.201602350

Welcome to the ITG

The Institute of Toxicology and Genetics (ITG) is a trans-disciplinary institute where biologists, chemists and physicists together aim to elucidate molecular and cellular interactions at functional interfaces. This knowledge guides the rational design and engineering of novel sophisticated tools for controlling the behaviour of cells in vivo and in vitro.
Our major topics are:

  • Cellular signalling Profile
  • Cell differentiation and proliferation 
  • Development and regeneration
  • Pathophysiology of diseases











International Master in Synthetic Biologie

Training and Research Program