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Strähle Lab - Recent Publications


  1. EmbryoMiner : A new framework for interactive knowledge discovery in large-scale cell tracking data of developing embryos.
    Schott, B.; Traub, M.; Schlagenhauf, C.; Takamiya, M.; Antritter, T.; Bartschat, A.; Löffler, K.; Blessing, D.; Otte, J. C.; Kobitski, A. Y.; Nienhaus, G. U.; Strähle, U.; Mikut, R.; Stegmaier, J.
    2018. PLoS Computational Biology, 14 (4), e1006128. doi:10.1371/journal.pcbi.1006128
  2. Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the co-factors in zebrafish.
    Weger, M.; Diotel, N.; Weger, B. D.; Beil, T.; Zaucker, A.; Eachus, H. L.; Oakes, J. A.; do Rego, J. L.; Storbeck, K.-H.; Gut, P.; Strähle, U.; Rastegar, S.; Müller, F.; Krone, N.
    2018. Journal of neuroendocrinology, 30 (4), Art.Nr.: e12586. doi:10.1111/jne.12586
  3. Zebrafish: A Pharmacogenetic Model for Anesthesia.
    Bedell, V.; Buglo, E.; Marcato, D.; Pylatiuk, C.; Mikut, R.; Stegmaier, J.; Scudder, W.; Wray, M.; Züchner, S.; Strähle, U.; Peravali, R.; Dallman, J. E.
    2018. Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A. Ed.: R. G. Eckenhoff, 189-209, Elsevier. doi:10.1016/bs.mie.2018.02.004
  4. Welches Tier interessiert die Medizin am meisten?.
    Strähle, U.
    2018. National geographic, (2), 24
  5. Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response.
    Paone, C.; Rudeck, S.; Etard, C.; Strähle, U.; Rottbauer, W.; Just, S.
    2018. Biochemical and biophysical research communications, 496 (2), 339-345. doi:10.1016/j.bbrc.2018.01.060
  6. Single Molecule Imaging Reveals Dysferlin-Mediated Recruitment of Phosphatidylserine in Cell Membrane Repair.
    Zhou, L.; Middel, V.; Strähle, U.; Nienhaus, G. U.
    2017. Biophysical journal, 12 (3), 146a-147a. doi:10.1016/j.bpj.2016.11.804
  7. A new framework for interactive knowledge discovery in large-scale trajectory data of zebrafish embryos.
    Schott, B.; Traub, M.; Antritter, T.; Schlagenhauf, C.; Takamiya, M.; Barschat, A.; Otte, J. C.; Kobitski, A.; Nienhaus, G. U.; Sanders, P.; Strähle, U.; Mikut, R.; Stegmaier, J.
    2017. 10th European Zebrafish Meeting, Budapest, H, July 3-7, 2017
  8. Interactive knowledge discovery in large-scale trajectory data of zebrafish embryos.
    Schott, B.; Traub, M.; Antritter, T.; Schlagenhauf, C.; Takamiya, M.; Barschat, A.; Otte, J. C.; Kobitski, A.; Nienhaus, G. U.; Sanders, P.; Strähle, U.; Mikut, R.; Stegmaier, J.
    2017. Seeing is Believing - Imaging the Processes of Life, EMBO/EMBL Symposium, Heidelberg, October 4-7, 2017
  9. Microtome-integrated microscope system for high sensitivity tracking of in-resin fluorescence in blocks and ultrathin sections for correlative microscopy.
    Lemercier, N.; Middel, V.; Hentsch, D.; Taubert, S.; Takamiya, M.; Beil, T.; Vonesch, J.-L.; Baumbach, T.; Schultz, P.; Antony, C.; Strähle, U.
    2017. Scientific reports, 7 (1), Art.Nr.: 13583. doi:10.1038/s41598-017-13348-6
  10. Report of Workshop on Euthanasia for Zebrafish : A Matter of Welfare and Science.
    Köhler, A.; Collymore, C.; Finger-Baier, K.; Geisler, R.; Kaufmann, L.; Pounder, K. C.; Schulte-Merker, S.; Valentim, A.; Varga, Z. M.; Weiss, J.; Strähle, U.
    2017. Zebrafish, 14 (6), 547-551. doi:10.1089/zeb.2017.1508
  11. Tracking of Indels by DEcomposition is a Simple and Effective Method to Assess Efficiency of Guide RNAs in Zebrafish.
    Etard, C.; Joshi, S.; Stegmaier, J.; Mikut, R.; Strähle, U.
    2017. Zebrafish, 14 (6), 586-588. doi:10.1089/zeb.2017.1454
  12. High-throughput screening and analysis of startle response behvior in zebrafish.
    Peravali, R.; Marcato, D.; Stegmaier, J.; Geisler, R.; Pylatiuk, C.; Reischl, M.; van Wezel, J.; Mikut, R.; Dallman, J.; Strähle, U.
    2017. 10th European Zebrafish Meeting, Budapest, H, July 3-7, 2017
  13. A smartphone-based photo motor response system.
    Pylatiuk, C.; Marcato, D.; Reichert, K. M.; Peravali, R.; Strähle, U.
    2017. 10th European Zebrafish Meeting, Budapest, H, July 3-7, 2017
  14. Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer.
    Cato, L.; Neeb, A.; Sharp, A.; Buzón, V.; Ficarro, S. B.; Yang, L.; Muhle-Goll, C.; Kuznik, N. C.; Riisnaes, R.; Rodrigues, D. N.; Armant, O.; Gourain, V.; Adelmant, G.; Ntim, E. A.; Westerling, T.; Dolling, D.; Rescigno, P.; Figueiredo, I.; Fauser, F.; Wu, J.; Rottenberg, J. T.; Shatkina, L.; Ester, C.; Luy, B.; Puchta, H.; Troppmair, J.; Jung, N.; Bräse, S.; Strähle, U.; Marto, J. A.; Nienhaus, G. U.; Al-Lazikani, B.; Salvatella, X.; Bono, J. S. de; Cato, A. C. B.; Brown, M.
    2017. eLife, 6, Art.Nr. e27159. doi:10.7554/eLife.27159
  15. Neuronales Flt1 steuert die Vaskularisierung des ZNS.
    Wild, R.; Klems, A.; Takamiya, M.; Hayashi, Y.; Strähle, U.; Ando, K.; Mochizuki, N.; Van Impel, A.; Schulte-Merker, S.; Krueger, J.; Preau, L.; Le Noble, F.
    2017. Vasomed, 29 (3), 145-146
  16. Fishing for contaminants : identification of three mechanism specific transcriptome signatures using Danio rerio embryos.
    Hausen, J.; Otte, J. C.; Legradi, J.; Yang, L.; Strähle, U.; Fenske, M.; Hecker, M.; Tang, S.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S. H.; Ottermanns, R.
    2017. Environmental science and pollution research, 25 (5), 4023-4036. doi:10.1007/s11356-017-8977-6
  17. Female versus male biological identities of nanoparticles determine the interaction with immune cells in fish.
    Hayashi, Y.; Miclaus, T.; Murugadoss, S.; Takamiya, M.; Scavenius, C.; Kjaer-Sorensen, K.; Enghild, J. J.; Strähle, U.; Oxvig, C.; Weiss, C.; Sutherland, D. S.
    2017. Environmental science / Nano, 4 (4), 895-906. doi:10.1039/C7EN00071E
  18. Protein-Functionalized DNA Nanostructures as Tools to Control Transcription in Zebrafish Embryos.
    Angelin, A.; Kassel, O.; Rastegar, S.; Strähle, U.; Niemeyer, C. M.
    2017. ChemistryOpen, 6 (1), 33–39. doi:10.1002/open.201600153
  19. Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization.
    Wild, R.; Klems, A.; Takamiya, M.; Hayashi, Y.; Strähle, U.; Ando, K.; Mochizuki, N.; van Impel, A.; Schulte-Merker, S.; Krueger, J.; Preau, L.; le Noble, F.
    2017. Nature Communications, 8, 13991. doi:10.1038/ncomms13991
  20. Archiving of zebrafish lines can reduce animal experiments in biomedical research.
    Geisler, R.; Köhler, A.; Dickmeis, T.; Strähle, U.
    2017. EMBO reports, 18 (1), 1-2. doi:10.15252/embr.201643561
  21. Automated feature detection and screening in zebrafish embryos.
    Pylatiuk, C.; Stegmaier, J.; Marcato, D.; Spomer, W.; Pfriem, A.; Reischl, M.; Alshut, R.; Mikut, R.; Peravali, R.; Strähle, U.
    2016. Fish and Amphibian Embryos as Alternatve Models in Toxicology and Teralogy : An International Symposium and Workshop, Aulnay-sour-Bois, F, December 1-2, 2016
  22. Euthanizing zebrafish legally in Europe – Are the approved methods of euthanizing zebrafish appropriate to research reality and animal welfare?.
    Valentim, A. M.; van Eeden, F. J.; Strähle, U.; Olsson, I. A. S.
    2016. EMBO reports, 17 (12), 1688–1689. doi:10.15252/embr.201643153
  23. A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi.
    Stoetzel, C.; Bär, S.; De Craene, J.-O.; Scheidecker, S.; Etard, C.; Chicher, J.; Reck, J. R.; Perrault, I.; Geoffroy, V.; Chennen, K.; Strähle, U.; Hammann, P.; Friant, S.; Dollfus, H.
    2016. Nature Communications, 7, Art. Nr. 13586. doi:10.1038/ncomms13586
  24. Report of the 4th European Zebrafish Principal Investigator Meeting.
    Lopes, S. S.; Distel, M.; Linker, C.; Fior, R.; Monteiro, R.; Bianco, I. H.; Portugues, R.; Strähle, U.; Saúde, L.
    2016. Zebrafish, 13 (6), 590-595. doi:10.1089/zeb.2016.1364
  25. Lmx1b is required for the glutamatergic fates of a subset of spinal cord neurons.
    Hilinski, W. C.; Bostrom, J. R.; England, S. J.; Juarez-Morales, J. L.; Jager, S. de; Armant, O.; Legradi, J.; Straehle, U.; Link, B. A.; Lewis, K. E.
    2016. Neural Development, 11 (1), Art.Nr.:16. doi:10.1186/s13064-016-0070-1
  26. Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair.
    Middel, V.; Zhou, L.; Takamiya, M.; Beil, T.; Shahid, M.; Roostalu, U.; Grabher, C.; Rastegar, S.; Reischl, M.; Nienhaus, G. U.; Strähle, U.
    2016. Nature Communications, 7, 12875. doi:10.1038/ncomms12875
  27. A compact unc45b-promoter drives muscle-specific expression in zebrafish and mouse.
    Rudeck, S.; Etard, C.; Khan, M. M.; Rottbauer, W.; Rudolf, R.; Strähle, U.; Just, S.
    2016. Genesis, 54 (8), 431–438. doi:10.1002/dvg.22953
  28. The Zebrafish as Model for Deciphering the Regulatory Architecture of Vertebrate Genomes.
    Rastegar, S.; Strähle, U.
    2016. Genetics, Genomics and Phenomics of Fish. Ed.: N.S. Foulkes, 195-216, Academic Press, Amsterdam. doi:10.1016/bs.adgen.2016.04.003
  29. Automation strategies for large-scale 3D image analysis.
    Stegmaier, J.; Schott, B.; Hübner, E.; Traub, M.; Shahid, M.; Takamiya, M.; Kobitski, A.; Hartmann, V.; Stotzka, R.; Van Wezel, J.; Streit, A.; Nienhaus, G. U.; Strähle, U.; Reischl, M.; Mikut, R.
    2016. Automatisierungstechnik, 64 (7), 555-566. doi:10.1515/auto-2016-0019
  30. Maintenance of Zebrafish Lines at the European Zebrafish Resource Center.
    Geisler, R.; Borel, N.; Ferg, M.; Maier, J. V.; Straehle, U.
    2016. Zebrafish, 13 (S1), S19-S23. doi:10.1089/zeb.2015.1205
  31. The in vitro PIG-A gene mutation assay: glycosylphosphatidylinositol (GPI)-related genotype-to-phenotype relationship in TK6 cells.
    Krüger, C. T.; Fischer, B. M.; Armant, O.; Morath, V.; Strähle, U.; Hartwig, A.
    2016. Archives of Toxicology, 90 (7), 1729-1736. doi:10.1007/s00204-016-1707-x
  32. HeRBi: Helmholtz Repository of Bioparts.
    Strähle, U.; Ferg, M.; Armant, O.; Gradl, M.; Kaufmann, L.; Rastegar, S.
    2016. Zebrafish, 13 (3), 234-235. doi:10.1089/zeb.2016.29003.str
  33. Super-resolution imaging of plasma membrane lesions inflicted by 405-nm laser light.
    Zhou, L.; Middel, V.; Nienhaus, U.; Strähle, U.
    2016. 60th Annual Meeting of the Biophysical Society, Los Angeles, CA, February 27 - March 2, 2016
  34. Whole transcriptome data analysis of zebrafish mutants affecting muscle development.
    Armant, O.; Gourain, V.; Etard, C.; Strähle, U.
    2016. Data in Brief, 8, 61-68. doi:10.1016/j.dib.2016.05.007
  35. Melanosomes in pigmented epithelia maintain eye lens transparency during zebrafish embryonic development.
    Takamiya, M.; Xu, F.; Suhonen, H.; Gourain, V.; Yang, L.; Yu Ho, N.; Helfen, L.; Schröck, A.; Etard, C.; Grabher, C.; Rastegar, S.; Schlunck, G.; Reinhard, T.; Baumbach, T.; Strähle, U.
    2016. Scientific reports, 6 (May), Art. Nr.: 25046. doi:10.1038/srep25046
  36. Zebrafish biosensor for toxicant induced muscle hyperactivity.
    Shahid, M.; Takamiya, M.; Stegmaier, J.; Middel, V.; Gradl, M.; Klüver, N.; Mikut, R.; Dickmeis, T.; Scholz, S.; Rastegar, S.; Yang, L.; Strähle, U.
    2016. Scientific Reports, 6, 23768. doi:10.1038/srep23768
  37. An automated and high-throughput photomotor response platform for chemical screens.
    Marcato, D.; Alshut, R.; Breitwieser, H.; Mikut, R.; Strähle, U.; Pylatiuk, C.; Peravali, R.
    2015. 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), Milano, I, August 25-29, 2015
  38. An automated and high-throughput photomotor response platform for chemical screens.
    Marcato, D.; Alshut, R.; Breitwieser, H.; Mikut, R.; Strähle, U.; Pylatiuk, C.; Peravali, R.
    2015. Proceedings of the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), Milano, I, August 25-29, 2015 Piscataway, N.J. : IEEE, 2015, 7728-7731. doi:10.1109/EMBC.2015.7320183
  39. Fold-change threshold screening: a robust algorithm to unmask hidden gene expression patterns in noisy aggregated transcriptome data.
    Hausen, J.; Otte, J. C.; Strähle, U.; Hammers-Wirtz, M.; Hollert, H.; Keiter, S. H.; Ottermanns, R.
    2015. Environmental Science and Pollution Research, 22, 16384-16392. doi:10.1007/s11356-015-5019-0
  40. Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells.
    Etard, C.; Armant, O.; Roostalu, U.; Gourain, V.; Ferg, M.; Strähle, U.
    2015. Genome Biology, 16 (1), 267/1-20. doi:10.1186/s13059-015-0825-8
  41. Differential expression of id genes and their potential regulator znf238 in zebrafish adult neural progenitor cells and neurons suggests distinct functions in adult neurogenesis.
    Diotel, N.; Beil, T.; Strähle, U.; Rastegar, S.
    2015. Gene Expression Patterns, 19 (1-2), 1-13. doi:10.1016/j.gep.2015.05.004
  42. Red light-regulated reversible nuclear localization of proteins in mammalian cells and Zebrafish.
    Beyer, H. M.; Juillot, S.; Herbst, K.; Samodelov, S. L.; Müller, K.; Schamel, W. W.; Römer, W.; Schäfer, E.; Nagy, F.; Strähle, U.; Weber, W.; Zurbriggen, M. D.
    2015. ACS Synthetic Biology, 4, 951-958. doi:10.1021/acssynbio.5b00004
  43. Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome.
    Naville, M.; Ishibashi, M.; Ferg, M.; Bengani, H.; Rinkwitz, S.; Krecsmarik, M.; Hawkins, T. A.; Wilson, S. W.; Manning, E.; Chilamakuri, C. S. R.; Wilson, D. I.; Louis, A.; Raymond, F. L.; Rastegar, S.; Strähle, U.; Lenhard, B.; Bally-Cuif, L.; van Heyningen, V.; FitzPatrick, D. R.; Becker, T. S.; Crollius, H. R.
    2015. Nature Communications, 6, 6904. doi:10.1038/ncomms7904
  44. Mutations in TUBGCP4 alter microtubule organization via the ?-tubulin ring complex in autosomal-recessive microcephaly with chorioretinopathy.
    Scheidecker, S.; Etard, C.; Haren, L.; Stoetzel, C.; Hull, S.; Arno, G.; Plagnol, V.; Drunat, S.; Passemard, S.; Toutain, A.; Obringer, C.; Koob, M.; Geoffroy, V.; Marion, V.; Strähle, U.; Ostergaard, P.; Verloes, A.; Merdes, A.; Moore, A. T.; Dollfus, H.
    2015. American Journal of Human Genetics, 96, 666-674. doi:10.1016/j.ajhg.2015.02.011
  45. The helix-loop-helix protein Id1 controls stem cell proliferation during regenerative neurogenesis in the adult zebrafish telencephalon.
    Rodriguez Viales, R.; Diotel, N.; Ferg, M.; Armant, O.; Eich, J.; Alunni, A.; März, M.; Bally-Cuif, L.; Rastegar, S.; Strähle, U.
    2015. Stem Cells, 33, 892-903. doi:10.1002/stem.1883
  46. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches.
    Diotel, N.; Rodriguez Vialez, R.; Armant, O.; März, M.; Ferg, M.; Rastegar, S.; Strähle, U.
    2015. Journal of Comparative Neurology, 523, 1202-1221. doi:10.1002/cne.23733
  47. Molecular description of eye defects in the zebrafish pax6b mutant, sunrise, reveals a pax6b-dependent genetic network in the developing anterior chamber.
    Takamiya, M.; Weger, B. D.; Schindler, S.; Beil, T.; Yang, L.; Armant, O.; Ferg, M.; Schlunck, G.; Reinhard, T.; Dickmeis, T.; Rastegar, S.; Strähle, U.; Leung, Y. F.
    2015. PLoS ONE, 10 (2), e0117645. doi:10.1371/journal.pone.0117645
  48. An ensemble-averaged, cell density-based digital model of zebrafish embryo development derived from light-sheet microscopy data with single-cell resolution.
    Kobitski, A. Y.; Otte, J. C.; Takamiya, M.; Schäfer, B.; Mertes, J.; Stegmaier, J.; Rastegar, S.; Rindone, F.; Hartmann, V.; Stotzka, R.; Garcia, A.; van Wezel, J.; Mikut, R.; Strähle, U.; Nienhaus, G. U.
    2015. Scientific Reports, 5 (8601), 1-10. doi:10.1038/srep08601
  49. Impacts of different exposure scenarios on transcript abundances in Danio rerio embryos when investigating the toxicological burden of riverine sediments.
    Bluhm, K.; Otte, J. C.; Yang, L.; Zinsmeister, C.; Legradi, J.; Keiter, S.; Kosmehl, T.; Braunbeck, T.; Strähle, U.; Hollert, H.
    2014. PLoS one, 9 (9), e106523. doi:10.1371/journal.pone.0106523
  50. Automated high-throughput and high-content screening platforms for toxicological studies in fish.
    Peravali, R.; Gursky, E.; Marcato, D.; Shahid, M.; Takamiya, M.; Stegmeier, J.; Breitwieser, H.; Pylatiuk, C.; Kobitsky, A.; Van Wezel, J.; Hartmann, V.; Nienhaus, G. U.; Mikut, R.; Straehle, U.
    2014. International Symposium & Workshop 'Fish and Amhibian Embryos as Alternative Models in Toxicology and Teratology', Paris, F, December 1-2, 2014
  51. Efficient extraction of cell shapes and nuclei from 3D light-sheet microscopy images.
    Stegmaier, J.; Amat, F.; Takamiya, M.; Bartschat, A.; Otte, J. C.; Kobitski, A.; Lemon, B.; McDole, K.; Wan, Y.; Nienhaus, G. U.; Strähle, U.; Keller, P. J.; Mikut, R.
    2014. BioImage Informatics Meeting, Leuven, B, October 8-10, 2014
  52. Stab wound injury of the Zebrafish adult telencephalon: A method to investigate vertebrate brain neurogenesis and regeneration.
    Schmidt, R.; Beil, T.; Strähle, U.; Rastegar, S.
    2014. Journal of Visualized Experiments, 90, e51753/1-8. doi:10.3791/51753
  53. Fast Segmentation of Stained Nuclei in Terabyte-Scale, Time Resolved 3D Microscopy Image Stacks.
    Stegmaier, J.; Otte, J. C.; Kobitski, A.; Bartschat, A.; Garcia, A.; Nienhaus, G. U.; Strähle, U.; Mikut, R.
    2014. PLoS ONE, 9 (2), e90036/1-11. doi:10.1371/journal.pone.0090036
  54. Der Zebrabärling als Modell für die Regeneration von Nervengewebe.
    Ferg, M.; Rastegar, S.; Strähle, U.
    2014. BIOspektrum, 2, 148-150. doi:10.1007/s12268-014-0419-0
  55. Gene transcription in the zebrafish embryo: regulators and networks.
    Ferg, M.; Armant, O.; Yang, L.; Dickmeis, T.; Rastegar, S.; Strähle, U.
    2014. Briefings in Functional Genomics, 13, 131-143. doi:10.1093/bfgp/elt044
  56. Two independent transcription initiation codes overlap on vertebrate core promoters.
    Haberle, V.; Li, N.; Hadzhiev, Y.; Plessy, C.; Previti, C.; Nepal, C.; Gehrig, J.; Dong, X.; Akalin, A.; Suzuki, A. M.; van Ijken, F. J.; Armant, O.; Ferg, M.; Strähle, U.; Carninci, P.; Müller, F.; Lenhard, B.
    2014. Nature, 507, 381-385. doi:10.1038/nature12974
  57. Exome sequencing of Bardet Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18).
    Scheidecker, S.; Etard, C.; Pierce, N. W.; Geoffroy, V.; Schaefer, E.; Muller, J.; Chennen, K.; Flori, E.; Pelletier, V.; Poch, O.; Marion, V.; Stoetzel, C.; Strähle, U.; Nachury, M. V.; Dollfus, H.
    2014. Journal of Medical Genetics, 51, 132-136. doi:10.1136/jmedgenet-2013-101785
  58. Automated prior knowledge-based quantification of neuronal patterns in the spinal cord of zebrafish.
    Stegmaier, J.; Shahid, M.; Takamiya, M.; Yang, L.; Rastegar, S.; Reischl, M.; Strähle, U.; Mikut, R.
    2014. Bioinformatics, 30, 726-733. doi:10.1093/bioinformatics/btt600
  59. Neurogenesis in zebrafish : from embryo to adult.
    Schmidt, R.; Strähle, U.; Scholpp, S.
    2013. Neural development, 8 (3). doi:10.1186/1749-8104-8-3
  60. Development of a digital microfluidic system for automated synthesis of DNA by interactive capped assembly.
    von der Ecken, S.; Ahrens, R.; Ferg, M.; Herbst, K.; Strähle, U.; Guber, A.
    2013. International Symposium on Synthetic Biology (SynBio 2013), Heidelberg, December 9-11, 2013
  61. Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis.
    Nepal, C.; Hadzhiev, Y.; Previti, C.; Haberle, V.; Li, N.; Takahashi, H.; Suzuki, A. M.; Sheng, Y.; Abdelhamid, R. F.; Anand, S.; Gehrig, J.; Akalin, A.; Kockx, C. E. M.; van der Sloot, A. A. J.; van Ijcken, W. F. J.; Armant, O.; Rastegar, S.; Watson, C.; Strähle, U.; Stupka, E.; Carninci, P.; Lenhard, B.; Müller, F.
    2013. Genome Research, 23, 1938-1950. doi:10.1101/gr.153692.112
  62. Glycolysis supports embryonic muscle growth by promoting myoblast fusion.
    Tixier, V.; Bataille, L.; Etard, C.; Jagla, T.; Weger, M.; DaPonte, J. P.; Strähle, U.; Dickmeis, T.; Jagla, K.
    2013. Proceedings of the National Academy of Sciences of the United States of America, 110, 18982-18987. doi:10.1073/pnas.1301262110
  63. realTox: Real-time imaging of toxicant impact in whole organisms at single cell resolution.
    Otte, J. C.; Kobitskiy, A.; Stegmaier, J.; Takamiya, M.; Hartmann, V.; Schäfer, B.; Garcia, A.; van Wezel, J.; Stotzka, R.; Nienhaus, G. U.; Mikut, R.; Strähle, U.
    2013. Jahrestagung der Deutschen Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie (DGPT), Halle, 5.-7. März 2013
  64. Light Sheet Microscope (LSM).
    Kobitskiy, A.; Nienhaus, G. U.; Otte, J. C.; Takamiya, M.; Strähle, U.; Stegmaier, J.; Mikut, R.
    2013. Data Life Cycle Lab. Key Technologies. Status 2013. Big Data in Science. Hrsg.: R. Stotzka, 8, Karlsruhe
  65. Automated processing of Zebrafish imaging data: A survey.
    Mikut, R.; Dickmeis, T.; Driever, W.; Geurts, P.; Hamprecht, F. A.; Kausler, B. X.; Ledesma-Carbayo, M. J.; Maree, R.; Mikula, K.; Pantazis, P.; Ronneberger, O.; Santos, A.; Stotzka, R.; Strähle, U.; Peyrieras, N.
    2013. Zebrafish, 10, 401-421. doi:10.1089/zeb.2013.0886
  66. Gene expression profiling in zebrafish embryos (Danio rerio) for detection of sediment-borne pollution.
    Otte, J. C.; Schiwy, S.; Keiter, S. H.; Hollert, H.; Strähle, U.
    2013. Abschlusssymposium des Projektes DanTox, RWTH Aachen, 10.Juni 2013
  67. Report of the second European Zebrafish principal investigator meeting in Karlsruhe, Germany, March 21-24, 2012.
    Cavodeassi, F.; Del Bene, F.; Fürthauer, M.; Grabner, C.; Herzog, W.; Lehtonen, S.; Linker, C.; Mercader, N.; Mikut, R.; Norton, W.; Strähle, U.; Tiso, N.; Foulkes, N. S.
    2013. Zebrafish, 10 (1), 119-123. doi:10.1089/zeb.2012.0829
  68. Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos.
    Armant, O.; März, M.; Schmidt, R.; Ferg, M.; Diotel, N.; Ertzer, R.; Bryne, J. C.; Yang, L.; Baader, I.; Reischl, M.; Legradi, J.; Mikut, R.; Stemple, D.; van Ilcken, W.; van der Sloot, A.; Lenhard, B.; Strähle, U.; Rastegar, S.
    2013. Developmental Biology, 380, 351-362. doi:10.1016/j.ydbio.2013.05.006
  69. Real-time in vivo monitoring of circadian E-box enhancer activity: A robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock.
    Weger, M.; Weger, B. D.; Diotel, N.; Rastegar, S.; Hirota, T.; Kay, S. A.; Strähle, U.; Dickmeis, T.
    2013. Developmental Biology, 380, 259-273. doi:10.1016/j.ydbio.2013.04.035
  70. Gene responses in the central nervous system of Zebrafish embryos exposed to the neurotoxicant methyl mercury.
    Ho, N. Y.; Yang, L.; Legradi, J.; Armant, O.; Takamiya, M.; Rastegar, S.; Strähle, U.
    2013. Environmental Science and Technology, 47, 3316-3325. doi:10.1021/es3050967
  71. Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development.
    Sanges, R.; Hadzhiev, Y.; Gueroult-Bellone, M.; Roure, A.; Ferg, M.; Meola, N.; Amore, G.; Basu, S.; Brown, E. R.; de Simone, M.; Petrera, F.; Licastro, D.; Strähle, U.; Banfi, S.; Lemaire, P.; Birney, E.; Müller, F.; Stupka, E.
    2013. Nucleic Acids Research, 41, 3600-3618. doi:10.1093/nar/gkt030
  72. A universal program for tissue regeneration?.
    Strähle, U.; Schmidt, R.
    2012. Developmental Cell, 23, 1123-1124. doi:10.1016/j.devcel.2012.11.016
  73. EuFishBioMed (COST Action BM0804): A european network to promote the use of small fishes in biomedical research.
    Strähle, U.; Bally-Cuif, L.; Kelsh, R.; Beis, D.; Mione, M.; Panula, P.; Figueras, A.; Gothilf, Y.; Brösamle, C.; Geisler, R.; Knedlitschek, G.
    2012. Zebrafish, 9, 90-93. doi:10.1089/zeb.2012.0742
  74. A combined DNA-microarray and mechanism-specific toxicity approach with zebrafish embryos to investigate the pollution of river sediments.
    Kosmehl, T.; Otte, J. C.; Yang, L.; Legradi, J.; Bluhm, K.; Zinsmeister, C.; Keiter, S. H.; Reifferscheid, G.; Manz, W.; Braunbeck, T.; Strähle, U.; Hollert, H.
    2012. Reproductive Toxicology, 33, 245-253. doi:10.1016/j.reprotox.2012.01.005
  75. NBP, a zebrafish homolog of human Kank3, is a novel Numb interactor essential for epidermal integrity and neurulation.
    Boggetti, B.; Jasik, J.; Takamiya, M.; Strähle, U.; Reugels, A. M.; Campos-Ortega, J. A.
    2012. Developmental Biology, 365, 164-174. doi:10.1016/j.ydbio.2012.02.021
  76. Laser ablation of the sonic hedgehog-a-expressing cells during fin regeneration affects ray branching morphogenesis.
    Zhang, J.; Jeradi, S.; Strähle, U.; Akimenko, M. A.
    2012. Developmental Biology, 365, 424-431. doi:10.1016/j.ydbio.2012.03.008
  77. In vivo imaging of molecular interactions at damaged sarcolemma.
    Roostalu, U.; Strähle, U.
    2012. Developmental Cell, 22, 515-529. doi:10.1016/j.devcel.2011.12.008
  78. Xirp proteins mark injured skeletal muscel in zebrafish.
    Otten, C.; van der Ven, P. F.; Lewrenz, I.; Paul, S.; Steinhagen, A.; Busch-Nentwich, E.; Eichhorst, J.; Wiesner, B.; Stemple, D.; Strähle, U.; Fürst, D. O.; Abdelilah-Seyfried, S.
    2012. PLoS one, 7 (2), e31041/1-14. doi:10.1371/journal.pone.0031041
  79. Zebrafish embryos as an alternative to animal experiments. A commentary on the definition of the onset of protected life stages in animal welfare regulations.
    Strähle, U.; Scholz, S.; Geisler, R.; Greiner, P.; Hollert, H.; Rastegar, S.; Schumacher, A.; Selderslaghs, I.; Weiss, C.; Witters, H.; Braunbeck, T.
    2012. Reproductive Toxicology, 33, 128-132. doi:10.1016/j.reprotox.2011.06.121
  80. Transcriptional response of Zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression.
    Klüver, N.; Yang, L.; Busch, W.; Scheffler, K.; Renner, P.; Strähle, U.; Scholz, S.
    2011. PLoS one, 6, e29063. doi:10.1371/journal.pone.0029063
  81. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects.
    Bloch-Zupan, A.; Jamet, X.; Etard, C.; Laugel, V.; Muller, J.; Geoffroy, V.; Strauss, J. P.; Pelletier, V.; Marion, V.; Poch, O.; Strähle, U.; Stoetzel, C.; Dollfus, H.
    2011. American Journal of Human Genetics, 89, 773-781. doi:10.1016/j.ajhg.2011.11.002
  82. Development of microscopy-based high-throughput toxicity assays in mammalian cells and in zebrafish embryos.
    Al-Rawi, M.; Schreck, I.; Diabate, S.; Guber, A.; Strähle, U.; Weiss, C.
    2011. Experimentelle und Klinische Pharmakologie und Toxikologie in Baden-Württemberg : 1.Wissenschaftliches Treffen, Schloss Reisensburg, Günzburg, 17.-19.November 2011
  83. Automation systems to enable high-throughput screening in zebrafish embryos.
    Pfriem, A.; Alshut, R.; Legradi, J.; Schulz, S.; Pylatiuk, C.; Liebel, U.; Strähle, U.; Reischl, M.; Bretthauer, G.; Mikut, R.
    2011. Experimentelle und Klinische Pharmakologie und Toxikologie in Baden-Württemberg : 1.Wissenschaftliches Treffen, Schloss Reisensburg, Günzburg, 17.-19.November 2011
  84. The zebrafish embryo model in toxicology and teratology, September 2-3, 2010, Karlsruhe Germany. Meeting report.
    Busch, W.; Duis, K.; Fenske, M.; Maack, G.; Legler, J.; Padilla, S.; Strähle, U.; Witters, H.; Scholz, S.
    2011. Reproductive Toxicology, 31, 585-588. doi:10.1016/j.reprotox.2011.02.010
  85. Regenerative response following stab injury in the adult Zebrafish telencephalon.
    März, M.; Schmidt, R.; Rastegar, S.; Strähle, U.
    2011. Developmental Dynamics, 240, 2221-2231. doi:10.1002/dvdy.22710
  86. The myosin-interacting protein SMYD1 is essential for sarcomere organization.
    Just, S.; Meder, B.; Berger, I. M.; Etard, C.; Trano, N.; Patzel, E.; Hassel, D.; Marquart, S.; Dahme, T.; Vogel, B.; Fishman, M. C.; Katus, H. A.; Strähle, U.; Rottbauer, W.
    2011. Journal of Cell Science, 124, 3127-3136. doi:10.1242/jcs.084772
  87. Selective immobilization of somic hedgehog on benzylguanine terminated patterned self-assembled monolayers.
    Kwok, C. W.; Strähle, U.; Zhao, Y.; Scharnweber, T.; Weigel, S.; Welle, A.
    2011. Biomaterials, 32, 6719-6728. doi:10.1016/j.biomaterials.2011.05.069
  88. Automatische Klassifikation von Bildzeitreihen für toxikologische Hochdurchsatz-Untersuchungen.
    Alshut, R.; Mikut, R.; Legradi, J.; Liebel, U.; Strähle, U.; Bretthauer, G.; Reischl, M.
    2011. at - Automatisierungstechnik, 59, 259-268. doi:10.1524/auto.2011.0921
  89. Stem cells, genetics and fish.
    Strähle, U.
    2010. Public service review: European science & technology, 2010 (7), 66-67
  90. Expression of the transcription factor Olig2 in proliferating cells in the adult zebrafish telencephalon.
    März, M.; Schmidt, R.; Rastegar, S.; Strähle, U.
    2010. Developmental Dynamics, 239, 3336-3349. doi:10.1002/dvdy.22455
  91. Conservation of shh cis-regulatory architecture of the coelecanth is consistent with its ancestral phylogenetic position.
    Lang, M.; Hadzhiev, Y.; Siegel, N.; Amemiya, C.; Parada, C.; Strähle, U.; Becker, M. B.; Müller, F.; Meyer, A.
    2010. EvoDevo, 1 (11). doi:10.1186/2041-9139-1-11
  92. Segmentation, feature extraction and data mining oof microscopic images.
    Reischl, M.; Alshut, R.; Liebel, U.; Strähle, U.; Rudolf, R.; Mikut, R.
    2010. Bio-Image Analysis Workshop, Karlsruhe, 1.Oktober 2010
  93. Automated evaluation of images and image sequences for high-throughput screening of zebrafish.
    Alshut, R.; Mikut, R.; Legradi, J.; Liebel, U.; Strähle, U.; Reischl, M.
    2010. The Zebrafish Embryo Model in Toxicology and Teratology, Karlsruhe, September 2- 3, 2010
  94. Report of the European zebrafish principal investigator meeting in Padua, Italy, March 18-20, 2010.
    Brennan, C.; Dosch, R.; Haramis, A. P.; Luckenbach, T.; Martinez-Morales, J. R.; Moro, E.; Polok, B.; Ramesh, T. M.; Russell, C.; Argenton, F.; Strähle, U.
    2010. Zebrafish, 7, 305-10. doi:10.1089/zeb.2010.0668
  95. Fundoscopy in adult zebrafish and its application to isolate mutant strains with ocular defects.
    Tschopp, M.; Takamiya, M.; Cerveny, K. L.; Gestri, G.; Biehlmaier, O.; Wilson, S. W.; Strähle, U.; Neuhauss, C. F.
    2010. PLoS One, 5 (11), e15427. doi:10.1371/journal.pone.0015427
  96. The chaperones Unc45b and Hsp90a are essential for folding of myosin from worms to men.
    Strähle, U.
    2010. The Norwegian Zebrafish Platform and the Zebrafish Network Norway ZNN Conf.and Annual Meeting, Oslo, N, October 29-31, 2010
  97. BioInterfaces: molecular and cellular interactions at functional interfaces.
    Strähle, U.
    2010. 3rd Internat.Seminar on Nanosciences and Nanotechnology, Habana, CU, September 6-10, 2010
  98. Sharing chemical libraries within the European zebrafish community.
    Grabher, C.; Patton, E. E.; Strähle, U.
    2010. Zebrafish, (Letter to the Editor), 7 (1), 83. doi:10.1089/zeb.2010.0651
  99. The zebrafish embryo as a model for assessing off-target drug effects.
    Strähle, U.; Grabher, C.
    2010. Disease Models and Mechanisms, 3, 689-92. doi:10.1242/dmm.006312
  100. Methods for automated high-throughput toxicity testing using Zebrafish embryos.
    Alshut, R.; Legradi, J.; Liebel, U.; Yang, L.; van Wezel, J.; Strähle, U.; Mikut, R.; Reischl, M.
    2010. Dillmann, R. [Hrsg.] KI 2010 : Advances in Artificial Intelligence ; Proc.of the 33rd Annual German Conf.on AI, Karlsruhe, September 21-24, 2010 Berlin [u.a.] : Springer, 2010 (Lecture Notes in Computer Science ; 6359 : Lecture Notes in Artificial Intelligence)
  101. Methods for automated high-throughput toxicity testing using Zebrafish embryos.
    Alshut, R.; Legradi, J.; Liebel, U.; Yang, L.; van Wezel, J.; Strähle, U.; Mikut, R.; Reischl, M.
    2010. Dillmann, R. [Hrsg.] KI 2010 : Advances in Artificial Intelligence ; Proc.of the 33rd Annual German Conf.on AI, Karlsruhe, September 21-24, 2010 Berlin [u.a.] : Springer, 2010 (Lecture Notes in Computer Science ; 6359 : Lecture Notes in Artificial Intelligence), 219-26
  102. Impacts of noxa on the early stages of vertebrate development: a systems biology approach.
    Otte, J. C.; Hartmann, V.; Pfeiffer, S.; Legradi, J.; Strähle, U.
    2010. The Zebrafish Embryo Model in Toxicology and Teratology, Karlsruhe, September 2-3, 2010
  103. Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: different toxicity and target gene expression.
    Wahl, M.; Guenther, R.; Yang, L.; Bergman, A.; Straehle, U.; Strack, S.; Weiss, C.
    2010. Toxicology Letters, 198, 119-26. doi:10.1016/j.toxlet.2010.06.001
  104. Evolution of the regulatory network controlling the differentiation of interneurons in the ventral spinal cord.
    Strähle, U.
    2010. 3rd EED Conf., Universite Paris Diderot, Paris, F, July 8-9, 2010
  105. DanTox - ein BMBF-Verbundprojekt zur Ermittlung spezifischer Toxizität und molekularer Wirkungsmechanismen sedimentgebundener Umweltschadstoffe mit dem Zebrabärbling (Danio rerio).
    Keiter, S.; Peddinghaus, S.; Feiler, U.; von der Goltz, B.; Hafner, C.; Ho, N. Y.; Rastegar, S.; Otte, J. C.; Ottermanns, R.; Reifferscheid, G.; Strähle, U.; Braunbeck, T.; Hammers-Wirtz, M.; Hollert, H.
    2010. Umweltwissenschaften und Schadstoff-Forschung, 22, 94-98. doi:10.1007/s12302-010-0119-4
  106. Regulatory interactions specifying Kolmer-Agduhr interneurons.
    Yang, L.; Rastegar, S.; Strähle, U.
    2010. Development, 137, 2713-22. doi:10.1242/dev.048470
  107. Methyl mercury suppresses the formation of the tail primordium in developing Zebrafish embryos.
    Yang, L.; Ho, N. Y.; Müller, F.; Strähle, U.
    2010. Toxicological Sciences, 115, 379-90. doi:10.1093/toxsci/kfq053
  108. DanTox - a novel joint research project using zebrafish (Danio reria) to identify specific toxicity and molecular modes of action of sediment-bound pollutants.
    Keiter, S.; Peddinghaus, S.; Feiler, U.; von der Goltz, B.; Hafner, C.; Ho, N. Y.; Rastegar, S.; Otte, J. C.; Ottermanns, R.; Reifferscheid, G.; Strähle, U.; Braunbeck, T.; Hammers-Wirtz, M.; Hollert, H.
    2010. Journal of Soils and Sediments, 10, 714-17. doi:10.1007/s11368-010-0221-7
  109. Lack of apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos.
    Etard, C.; Roostalu, U.; Strähle, U.
    2010. Journal of Cell Biology, 189, 527-39. doi:10.1083/jcb.200912125
  110. Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon.
    März, M.; Chapouton, P.; Diotel, N.; Vaillant, C.; Hesl, B.; Takamiya, M.; Lam, C. S.; Kah, O.; Bally-Cuif, L.; Strähle, U.
    2010. GLIA, 58, 870-88. doi:10.1002/glia.20971
  111. Automated readout of zebrafish assays by means of automated microscopy and image processing.
    Reischl, M.; Alshut, R.; Legradi, J.; Strähle, U.; Bretthauer, G.; Mikut, R.; Liebel, U.
    2010. 1st European Zebrafish Meeting, Padova, I, March 18-21, 2010 Book of Abstracts
  112. The role of the chaperones Unc45b, Hsp90a and the cytidine deaminase Apobec2 in muscle development and maintenance.
    Strähle, U.
    2010. 11th Australia and New Zealand Zebrafish Workshop, Sydney, AUS, February 3-5, 2010
  113. The zebrafish embryo as model for high throughput and high resolution imaging.
    Strähle, U.
    2009. 1st Meeting on Emerging Technologies in Zebrafish, Bilbao, E, November 25-26, 2009
  114. Das Programm BioInterfaces. Ein Aspekt: Der Zebrabärbling als Modell der Systembiologie.
    Strähle, U.
    2009. VIM-Kolloquium, Karlsruhe, 1.Oktober 2009
  115. Robust identification of coagulated zebrafish eggs using image processing and classification techniques.
    Alshut, R.; Legradi, J.; Yang, L.; Strähle, U.; Mikut, R.; Reischl, M.
    2009. Hoffmann, F. [Hrsg.] Proc.19.Workshop Computational Intelligence, Dortmund, 2.-4.Dezember 2009 Karlsruhe : KIT Scientific Publishing, 2009 (Schriftenreihe des Instituts für Angewandte Informatik/Automatisierungstechnik Karlsruher Institut für Technologie (KIT) ; Bd.29)
  116. Robust Identification of Coagulated Zebrafish Eggs using Image Processing and Classification Techniques.
    Alshut, R.; Legradi, J.; Yang, L.; Strähle, U.; Mikut, R.; Reischl, M.
    2009. Proceedings. 19. Workshop Computational Intelligence, Dortmund, 2. - 4. Dezember 2009. Hrsg.: F. Hoffmann, 9 - 21, Universitätsverl. Karlsruhe, Karlsruhe
  117. Zebrafish embryos as models for embryotoxic and teratological effects of chemicals.
    Yang, L.; Ho, N. Y.; Alshut, R.; Legradi, J.; Weiss, C.; Reischl, M.; Mikut, R.; Liebel, U.; Müller, F.; Strähle, U.
    2009. Reproductive Toxicology, 28, 245-53. doi:10.1016/j.reprotox.2009.04.013
  118. Barcode-like toxicogenomic profiles identify several hundred genes that respond to environmental toxicants in the zebrafish embryo.
    Strähle, U.; Yang, L.; Ho, C.
    2009. 46th Congress of the European Societies of Toxicology (EUROTOX 2009), Dresden, September 13-16, 2009 Toxicology Letters, 189(2009) Suppl.1, (Abstract)
  119. Zebrafish as a toxicogenomic model of the effects of chemicals on the developing vertebrate embryo.
    Strähle, U.
    2009. 46th Congress of the European Societies of Toxicology (EUROTOX 2009), Dresden, September 13-16, 2009
  120. Barcode-like toxicogenomic profiles identify several hundred genes that respond to environmental toxicants in the zebrafish embryo.
    Strähle, U.; Yang, L.; Ho, C.
    2009. Toxicology Letters, 46th Congress of the European Societies of Toxicology (EUROTOX 2009), Dresden, September 13-16, 2009, Suppl.1, (Abstract), 189, S50
  121. gfap and nestin reporter lines reveal characteristics of neural progenitors in the adult zebrafish brain.
    Lam, C. S.; März, M.; Strähle, U.
    2009. Developmental Dynamics, 238, 475-86. doi:10.1002/dvdy.21853
  122. Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: different toxicity and target gene expression.
    Wahl, M.; Guenther, R.; Yang, L.; Straehle, U.; Weiss, C.; Strack, S.
    2008. 49th Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie Mainz, March 11-13, 2008 Naunyn-Schmiedeberg's Archives of Pharmacology, 377(2008) Suppl. (Abstract)
  123. Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: different toxicity and target gene expression.
    Wahl, M.; Guenther, R.; Yang, L.; Straehle, U.; Weiss, C.; Strack, S.
    2008. Naunyn-Schmiedeberg's Archives of Pharmacology, 49th Annual Meeting Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie Mainz, March 11-13, 2008, Suppl. (Abstract), 377, 86
  124. Identification of gene networks involved in retinoic acid control of muscle differentiation.
    Genet, C.; Yang, L.; San Cristobal, M.; Jaekel, J.; Hamade, A.; Bonnieu, A.; Strähle, U.; Cousin, X.
    2008. 9th Internat.Symp.on Genetics in Aquaculture (ISGA), Montpellier, F, June 26-30, 2006 Aquaculture, 272(2007) Suppl.1., (abstract)
  125. A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity.
    Wahl, M.; Lahni, B.; Guenther, R.; Kuch, B.; Yang, L.; Strähle, U.; Strack, S.; Weiss, C.
    2008. Chemosphere, 73, 209-15. doi:10.1016/j.chemosphere.2008.05.025
  126. The words of the regulatory code are arranged in a variable manner in highly conserved enhancers.
    Rastegar, S.; Hess, I.; Dickmeis, T.; Nicod, J. C.; Ertzer, R.; Hadzhiev, Y.; Thies, W. G.; Scherer, G.; Strähle, U.
    2008. Developmental Biology, 318, 366-77. doi:10.1016/j.ydbio.2008.03.034
  127. The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis.
    Hawkins, T. A.; Haramis, A. P.; Etard, C.; Prodromou, C.; Vaughan, C. K.; Ashworth, R.; Ray, S.; Behra, M.; Holder, N.; Talbot, W. S.; Pearl, L. H.; Strähle, U.; Wilson, S. W.
    2008. Development, 135, 1147-56. doi:10.1242/dev.018150
  128. Rasl 11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype.
    Pezeron, G.; Lambert, G.; Dickmeis, T.; Strähle, U.; Rosa, F. M.; Mourrain, P.
    2008. PLoS One, 3 (1), e1434
  129. Shuttling of the chaperones Unc45b and Hsp90a between the A-band and the Z-line of the myofibril.
    Etard, C.; Roostalu, U.; Strähle, U.
    2008. Journal of Cell Biology, 180, 1163-75. doi:10.1083/jcb.200709128
  130. Conserved non-coding sequences and transcriptional regulation.
    Strähle, U.; Rastegar, S.
    2008. Brain Research Bulletin, 75, 225-30. doi:10.1016/j.brainresbull.2007.11.010
  131. Shuttling of the chaperones Unc45b and Hsp90a between the A-band and the Z-line of the myofibril.
    Etard, C.; Roostalu, U.; Strähle, U.
    2008. 1st Zebrafish Meeting, Veysonnaz, CH, March 14-15, 2008
  132. Sequential and cooperative action of Fgfs and Shh in the zebrafish retina.
    Vinothkumar, S.; Rastegar, S.; Takamiya, M.; Ertzer, R.; Strähle, U.
    2008. Developmental Biology, 314, 200-214. doi:10.1016/j.ydbio.2007.11.034
  133. Identification of gene networks involved in retinoic acid control of muscle differentiation.
    Genet, C.; Yang, L.; San Cristobal, M.; Jaekel, J.; Hamade, A.; Bonnieu, A.; Strähle, U.; Cousin, X.
    2007. Aquaculture, 272 (1), S260. doi:10.1016/j.aquaculture.2007.07.069
  134. Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo.
    Yang, L.; Kemadjou, J. R.; Zinsmeister, C.; Bauer, M.; Legradi, J.; Müller, F.; Pankratz, M.; Jäkel, J.; Strähle, U.
    2007. Genome Biology, R227, 8 (10). doi:10.1186/gb-2007-8-10-r227
  135. The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish.
    Ferg, M.; Sanges, R.; Gehrig, J.; Kiss, J.; Bauer, M.; Lovas, A.; Szabo, M.; Yang, L.; Strähle, U.; Pankratz, M. J.; Olasz, F.; Stupka, E.; Müller, F.
    2007. EMBO Journal, 26, 3945-56. doi:10.1038/sj.emboj.7601821
  136. Regulation der Genexpression.
    Strähle, U.; März, M.; Rathnam, S.; Rastegar, S.
    2007. Nachrichten - Forschungszentrum Karlsruhe, 39, 133-39
  137. Biologie im Forschungszentrum Karlsruhe.
    Strähle, U.
    2007. Nachrichten - Forschungszentrum Karlsruhe, 39, 91-92
  138. Functional diversification of sonic hedgehog paralog enhancers identified by phylogenomic reconstruction.
    Hadzhiev, Y.; Lang, M.; Ertzer, R.; Meyer, A.; Strähle, U.; Müller, F.
    2007. Genome Biology, R106, 8
  139. The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis.
    Etard, C.; Behra, M.; Fischer, N.; Hutcheson, D.; Geisler, R.; Strähle, U.
    2007. Developmental Biology, 308, 133-43. doi:10.1016/j.ydbio.2007.05.014
  140. Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish.
    Hadzhiev, Y.; Lele, Z.; Schindler, S.; Wilson, S. W.; Ahlberg, P.; Strähle, U.; Müller, F.
    2007. BMC Developmental Biology, 7, 75
  141. AHR signalling is not induced by polybrominated diphenyl ether (BDE 47) in rat hepatoma cells.
    Wahl, M.; Günther, R.; Yang, L.; Strähle, U.; Weiss, C.; Strack, S.
    2007. 48.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 13.-15.März 2007 Naunyn-Schmiedebergs Archives of Pharmacology, 375(2007) Suppl.1, (Abstract)
  142. AHR signalling is not induced by polybrominated diphenyl ether (BDE 47) in rat hepatoma cells.
    Wahl, M.; Günther, R.; Yang, L.; Strähle, U.; Weiss, C.; Strack, S.
    2007. Naunyn-Schmiedeberg's Archives of Pharmacology, 48.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 13.-15.März 2007, Suppl.1, (Abstract), 375, 101
  143. Cooperation of sonic hedgehog enhancers in midline expression.
    Ertzer, R.; Müller, F.; Hadzhiev, Y.; Rathnam, S.; Fischer, N.; Rastegar, S.; Strähle, U.
    2007. Developmental Biology, 301, 578-89. doi:10.1016/j.ydbio.2006.11.004
  144. Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon.
    Adolf, B.; Chapouton, P.; Lam, C. S.; Topp, S.; Tannhäuser, B.; Strähle, U.; Götz, M.; Bally-Cuif, L.
    2006. Developmental Biology, 295, 278-93. doi:10.1016/j.ydbio.2006.03.023
  145. Der Zebrabärbling als Modell der Entwicklung und Regeneration.
    Strähle, U.; Rastegar, S.; Etard, C.; Weg-Remers, S.; Müller, F.
    2006. Nachrichten - Forschungszentrum Karlsruhe, 38, 93-95
  146. Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish.
    Ninkovic, J.; Folchert, A.; Makhankov, Y. V.; Neuhauss, S. C. F.; Sillaber, I.; Strähle, U.; Bally-Cuif, L.
    2006. Journal of Neurobiology, 66, 463-75. doi:10.1002/neu.20231
  147. The homeobox gene irx1a is required for the propagation of the neurogenic waves in the zebrafish retina.
    Cheng, C. W.; Yan, C. H. M.; Hui, C. C.; Strähle, U.; Cheng, S. H.
    2006. Mechanisms of Development, 123, 252-63. doi:10.1016/j.mod.2005.12.001
  148. Four-dimensional imaging and quantification of gene expression in early developing zebrafish (Danio rerio) embryos.
    Yu, R. M. K.; Lin, C. C.; Chan, P. K.; Chow, E. S. H.; Murphy, M. B.; Chan, B. P.; Müller, F.; Strähle, U.; Cheng, S. H.
    2006. Toxicological Sciences, 90, 529-38. doi:10.1093/toxsci/kfj115
  149. Distribution of cannabinoid receptor 1 in the CNS of zebrafish.
    Lam, C. S.; Rastegar, S.; Strähle, U.
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  150. Mutation in the δ-subunit of the nAChR suppresses the muscle defects caused by lack of Dystrophin.
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  151. Assembly of trigeminal sensory ganglia by chemokine signalling.
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    2005. Neuron, 47, 653-66
  152. Enhancer sequence conservation between vertebrates is favoured in developmental regulator genes.
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    2005. Trends in Genetics, 21, 207-10. doi:10.1016/j.tig.2005.02.006
  153. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP.
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    2005. European Journal of Neuroscience, 21, 1758-62. doi:10.1111/j.1460-9568.2005.03988.x
  154. Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones.
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    2005. Development, 132, 645-58
  155. Development of the primary nervous system of the Zebrafish embryo.
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  156. Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models.
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    2005. BioEssays, 27, 189-200. doi:10.1002/bies.20153
  157. Conserved and acquired features of neurogenin1 regulation.
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    2004. Development, 131, 5627-37. doi:10.1242/dev.01455
  158. The basic helix-loop-helix proteins in vertebrate and invertebrate neurogenesis.
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  159. Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina.
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    2004. Development, 131, 3849-58. doi:10.1242/dev.01247
  160. Her5 acts as a prepattern factor that blocks neurogenin1 and coe2 expression upstream of Notch to inhibit neurogenesis at the midbrain-hindbrain boundary.
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    2004. Development, 131, 1993-2006
  161. Vertebrate floor-plate specification: variations on common themes.
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    2004. Trends in Genetics, 20, 155-62. doi:10.1016/j.tig.2004.01.002
  162. The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors.
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    2004. Toxicological Sciences, 77, 325-33. doi:10.1093/toxsci/kfh020
  163. Transposition and targeting of the prokaryotic mobile element IS30 in zebrafish.
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    2003. FEBS Letters, 550, 46-50
  164. Cyclops-independent floor plate differentiation in zebrafish embryos.
    Albert, S.; Müller, F.; Fischer, N.; Biellmann, D.; Neumann, C.; Blader, P.; Strähle, U.
    2003. Developmental Dynamics, 226, 59-66
  165. A floor plate enhancer of the Zebrafish netrin1 gene requires cyclops (nodal) signalling and the winged helix transcription factor foxA2.
    Rastegar, S.; Albert, S.; Le Roux, I.; Fischer, N.; Blader, P.; Müller, F.; Strähle, U.
    2003. Developmental Biology, (2002), 252, 1-14
  166. Search for enhancers: teleost models in comparative genomic and transgenic analysis of cis regulatory elements.
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    2002. BioEssays, 24, 564-72