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Christine Blattner - Publications (selected):

Solozobova V, Blattner C. Regulation of p53 in embryonic stem cells. (2010) Exp. Cell Res. 316, 2434-2446

Kulikov R, Maurit K, Grossman S, Arts J, Blattner C. (2010) Mdm2 facilitates the association of p53 with the proteasome. Proc. Natl. Acad. Sci. USA, 107, 10038-10043

Oberle C, Blattner C. (2010) Regulation of the DNA damage response to DSBs by post-translational modifications. Current Genomics, 8 4, 184-198

Boehme K, Blattner C. (2010) Regulation of p53 activity. Curr. Chem. Biol., 4, 01-12.

Boehme K, Blattner C. (2009) Regulation of p53 – Insights into a complex process. Crit. Rev. Biochem. Mol. Biol. 44, 367-392.

Solozobova V, Rolletschek A, Blattner C. (2009) Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage. BMC Cell Biol. 10, 46.

Blattner C. (2008) Junk DNA meets the p53 network. Mol. Syst. Biol, 4, (accepted)

Blattner C. (2008) Regulation of p53: The next generation. Cell Cycle, 7, 3149-3153.

Coin F, Okshenych V, Mocquet V, Groh S, Blattner C, Egly JM. (2008) Nucleotide excision repair driven by the dissociation of CAK from TFIIH. Mol. Cell, 31, 9-20.

Boehme KA, Kulikov R, Blattner C. (2008) p53 stabilization in response to DNA damage requires Akt/PPKB and DNA-PK. Proc. Natl. Acad. Sci. USA, 22, 7785-7790.

Jin Y, Zeng SX, Sun X_X, Lee H, Blattner C, Xiao Z, Lu H. (2008) MDMX promotes proteasomal turnover of p21 at G1 and early S-phases independently of, but in cooperation with, Mdm2. Mol. Cell. Biol., 28, 1218-1229.

Kulikov R, Winter M, Blattner C. (2006) Binding of p53 to the central domain of Mdm2 is regulated by phosphorylation. J. Biol. Chem., 281, 28575-83.

Kulikov R, Boehme AK, Blattner C. (2005) GSK-3 phosphorylates Mdm2 and regulates the turnover of the p53 tumor suppressor protein. Mol. Cell. Biol., 25, 7170-7180.

Winter M, Milne D, Kulikov R, Knippschild U, Meek D, Blattner C. (2004) Protein kinase CKI phosphorylates key sites in the acidic domain of Mdm2 in vitro and in vivo. Biochemistry, 43, 16356-16364.

Glockzin S, Ogi F, Hengstermann A, Scheffner M, Blattner C. (2003) Stabilization of polyubiquitinated forms of p53 by the DNA repair protein hHR23. Mol. Cell. Biol., 23, 8960-8969.

Blattner C, Winter M, Kulikov R. (2003) p53 stabilization and the role of radiation-induced signalling. In: Life Sciences and Radiation, (Kiefer, J., ed.) Springer Verlag., 92-99.

Blattner C, Herrlich P (2002) Radiation-induced activation of signal transduction. In: Handbook of cellular signalling, (Fornace A., ed.), Academic press, San Diego. 2, 257-262.

Blattner C, Hay T, Meek D, Lane DP. (2002) Hypophosphorylation of Mdm2 augments p53 stability. Mol. Cell. Biol., 22, 6170-6182.

Hietanen S, Lain S, Krauß E, Blattner C, and Lane DP. (2000) Activation of p53 in cervical carcinoma cells by small molecules. Proc. Natl. Acad. Sci. USA, 97, 8501-8506.

Blattner C, Tobiasch E, Litfin M, Rahmsdorf HJ, Herrlich P. (1999) DNA damage-induced p53 stabilization: no indication for an involvement of p53 phosphorylation. Oncogene, 18, 1723-1732.

Blattner C, Sparks A, Lane DP. (1999) Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol. Cell. Biol., 19, 3704-3713.

Herrlich P, Bender K, Knebel A, Böhmer FD, Gross S, Blattner C, Rahmsdorf HJ, Göttlicher M. (1999) Radiation-induced signal transduction: Mechanisms and consequences. C.R. Acad. Sci., III 2-3, 121-125.

Blattner C, Bender K, Herrlich P, Rahmsdorf HJ. (1998) Photoproducts in transcriptionally active DNA induce signal transduction to the delayed UV-responsive genes for collagenase and metallothionein. Oncogene, 16, 2827- 2834.

Herrlich P, Rahmsdorf HJ, Bender K, Blattner C, Knebel A. (1997) Signal transduction induced by adverse agents: "activation by inhibition". The UV response 1997. In: Molecular Biology of the toxic response (Puga and Wallace, eds) Taylor & Francis Washington DC, chapter 28.

Bender K, Blattner C, Knebel A, Iordanov M, Herrlich P, Rahmsdorf HJ. (1997) UV-induced signal transduction. J. Photochem. Photobiol., B. 37, 1-17.

Herrlich P, Blattner C, Knebel A, Bender K, Rahmsdorf HJ. (1997) Nuclear and non-nuclear targets of genotoxic agents in the induction of gene expression. Shared principles in yeast rodents, men and plants. Biol. Chem., 378, 1217-1229.

Rahmsdorf HJ, Sachsenmaier C, Radler-Pohl A, Blattner C, van Dam H, Herrlich P. (1995) Radiation-induced signal transduction. Radiation Res., 141, 108-111.

Blattner C, Knebel A, Radler-Pohl A, Sachsenmaier C, Herrlich P, Rahmsdorf HJ. (1994) DNA-damaging agents and growth factors induce changes in the program of expressed gene-products through common routes. Environmental and Molecular Mutagenesis, 24, 3-10.

 

 

Updated: January 29, 2010