Group Leader: Steffen Scholpp
tel.: + 44 (0) 1392 727451
A key feature of brain development is the formation of cellular compartments and their maintenance by boundaries. These tissue compartments establish a specific pattern of cellular recognition by different adhesive properties. The compartment boundaries emit morphogenetic signals responsible for organising local development. Work in the last two decades has led to a broad understanding of the developmental plan of the midbrain and hindbrain region, whereas the forebrain remains less understood due to its complexity.
Recently, we identified a new local organiser in the forebrain, and we termed it the mid-diencephalic organiser (MDO).
By using zebrafish as model organism, we have started to unravel specific organising functions for this structure and it turns out that the MDO is crucial for the development of the thalamus - the major relay station in the vertebrate brain.
Pictures from our workshop: Heads in the Wnt together with the Davidson group (KIT)
and the Carl group (Uni Heidelberg)
For more information visit the Scholpp Lab Wiki.
Our research projects are funded by:
Updated: January 23, 2018